Lapase

Pronunciation: a-mah-LASE/LYE-pase/PRO-tee-ase
Generic Name: Amylase/Lipase/Protease
Brand Name: Examples include Dygase and Lapase

Lapase is used for:

Relieving symptoms of indigestion (eg, feeling of fullness, gas, bloating) that occur after meals.

Lapase is a digestive enzyme combination. It works by helping the body to digest protein, starch, and fat.

Do NOT use Lapase if:

• you are allergic to any ingredient in Lapase or to pork protein


• you have inflammation of the pancreas (pancreatitis) or a flare-up of long-term pancreas problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lapase:

Some medical conditions may interact with Lapase. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of pancreas problems, stomach or bowel problems (eg, blockage, short bowel syndrome), or cystic fibrosis

Some MEDICINES MAY INTERACT with Lapase. However, no specific interactions with Lapase are known at this time.

Ask your health care provider if Lapase may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lapase:

Use Lapase as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Lapase by mouth with each meal or snack as directed by your doctor.


• Swallow Lapase whole. Do not break, crush, or chew before swallowing. If you cannot swallow the capsule whole, you may open it and sprinkle the contents over food. Mix the medicine with the food and swallow the entire mixture right away, followed by a glass of water.


• If you open the capsule, do not breathe in the powder. Some patients may experience an asthma attack or severe allergic reaction (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue) from breathing in the powder.


• If you miss a dose of Lapase, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once or take a dose without a snack or a meal.

Ask your health care provider any questions you may have about how to use Lapase.

Important safety information:

• This product may contain tartrazine dye (FD&C Yellow No. 5). This may cause an allergic reaction in some patients. If you have ever had an allergic reaction to tartrazine, ask your pharmacist if your product has tartrazine in it.


• Contact your doctor if you have loose stools while you take Lapase. Your doctor may need to decrease your dose


• PREGNANCY and BREAST-FEEDING: It is not known if Lapase can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lapase while you are pregnant. It is not known if Lapase is found in breast milk. If you are or will be breast-feeding while you use Lapase, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Lapase:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with Lapase. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or persistent loose stools; severe stomach pain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Lapase side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org), or emergency room immediately. Symptoms may include diarrhea.

Proper storage of Lapase:

Store Lapase at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lapase out of the reach of children and away from pets.

General information:

• If you have any questions about Lapase, please talk with your doctor, pharmacist, or other health care provider.


• Lapase is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lapase. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lapase resources

• Lapase Side Effects (in more detail)
• Lapase Use in Pregnancy & Breastfeeding
• Lapase Drug Interactions
• Lapase Support Group
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